Platelet to White Blood Cell Ratio (PWR) to Predict Mortality in Acute on Chronic Liver Failure of Cirrhosis Patient: A Systematic Review

Background: Liver cirrhosis (LC) is still being important public health concern, due to the rising of global incidence and mortality. There risk progression in LC patients acute-on-chronic liver failure (ACLF) with high complication short-term mortality rate. It needs rapid simpler predictor immediate accurate triage patient. The aim this study review systematically role PWR predict ACLF patient.Method: This systematic was identified by searching Pub-Med, Cochrane library, EMBASE database (2016-2022). Only observational studies were included. patient selected as main subject each study, added predictor. Cochran seven step model used perform review.Results: Six cohort retrospective met inclusion criteria, including total 1,348 ACLF. Half included had level evidence. non-survivor significantly lower values than survivor. range HR 0.665-0.995, p value 0.0001. Whereas cutoff non survivor 7.83-14.2.Conclusion: a predictive efficacy, similar CLIF-SOFA MELD score terms predicting patients. showed independent factor short term cirrhotic